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Relationship between endogenous sex hormone levels, lipoproteins and coronary atherosclerosis in males undergoing coronary angiography. Basaria S, Dobs AS. Risks versus advantages of testosterone remedy in elderly males. Scientific and technological providers and analysis and design relating thereto; industrial analysis and research services; design and growth of pc hardware and software program.
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Anabolic androgenic steroid use has increased over the previous decade, despite its potential for adverse effects. They proceed for use by Olympic stage athletes, and have even spread to highschool stage athletes, noncompetitive bodybuilders and leisure athletes (Sullivan et al 1998; Dhar et al 2007). Unfortunately, the info on the use of excessive dose anabolic steroids in humans are primarily offered as case stories or small research that lack sufficient control teams.
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We report a case of an acute ST-segment elevation myocardial infarction in a affected person with traditional cardiac risk elements utilizing supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person also had polycythemia, probably secondary to high-dose testosterone. The affected person underwent profitable percutaneous intervention of the proper coronary artery. Physicians and sufferers ought to be aware of the clinical consequences of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996). Moreover, a part of endothelial dysfunction has been proposed, which may contribute to abnormal vessel reactivity. However, testosterone in physiologic doses might even be beneficial in patients with angina , have greater ischemic thresholds and improved quality of life .
Acute myocardial infarction in a 22-year-old world class weight lifter using anabolic steroids. Men with coronary artery disease have lower levels of androgens than men with regular coronary angiograms. A left anterior oblique view of the right coronary artery after percutaneous intervention.
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